Types of Submissions and Reviews

Types of Submissions

New Protocols

The approval process for new proposals typically takes 4-6 weeks. Once approved, an Institutional Animal Care and Use Committee (IACUC) protocol is valid for 1 year past the initial approval date. A continuation or a de novo review must be submitted a minimum of 4-8 weeks prior to expiration of the protocol.

Continuations

On an annual basis, principal investigators (PIs) are required to submit continuations for each approved protocol. Continuations are due at least four weeks prior to the anniversary of the initial approval date.

De Novo Reviews

All protocols must receive a complete review once every three years. PIs must submit the GW IACUC application at least eight weeks prior to protocol expiration. The approval process for de novo reviews typically takes 6-8 weeks.

Addenda

Should a PI decide that they wish to make changes to their approved IACUC protocol, they must submit a GW IACUC modification. For addendums that receive Full Committee Review (FCR) or Designated Member Review (DMR) due to significant changes, the approval process generally takes 4-6 weeks. Approval for minor changes typically occurs within 2-3 weeks.

Types of Review

Upon receipt, IACUC administrative staff will review the submission to determine the appropriate level of review:

Full Committee Review (FCR)

  • Any protocols involving a USDA-covered species
  • Requires a veterinary review by the Attending Veterinarian or their designee
  • 6-8 weeks from submission to approval

Administrative Review (AR)

Designated Member Review (DMR)

  • Protocols not receiving FCR but also not eligible for AR
  • IACUC requires veterinary review for new protocols, de novo reviews, and submissions that include significant changes as defined in the IACUC Policy on Animal Protocol Submission and Review (GW login required)
  • Any IACUC member may request a FCR during the comment period
  • If no committee member requests a FCR, the IACUC Chair will appoint an IACUC member to serve as the primary reviewer
  • 1-2 weeks from submission to approval